Biochemistry (Including Placement Year) - BSc (Hons)

University of Essex

Develop your skillset and boost your CV. This module prepares you for the coursework, laboratory practicals and research projects that you will encounter during undergraduate study. Get to know referencing systems and learn how to effectively communicate scientific information. Use scientific units and simple algebra and demonstrate understanding of logarithms, exponentials, geometry and elementary calculus. Learn how to design experiments, handle data and display, interpret and analyse basic statistics. Teaching and learning will be through a mixture of lectures, classes, practicals and tutorials, with an emphasis on developing the key transferable skills needed for a career in biosciences.

Many recent advances in biological research have been born from an increased understanding of the molecules involved in systems and processes. But what do things look like beyond molecular level?

Study how molecules are formed from individual atoms, and how the properties of these constituent atoms influence molecular structure and reactivity. Examine the fundamental concepts of chemical bonding, electronegativity, acidity, basicity, hydrogen bonding and review the common organic functional groups and different types of isomerism.

Explore the building blocks of life. From the proteins that make up our genetic code to the lipids that envelope our cells, explore the structure, function and biological role of the major macromolecules. You investigate the basic principles of protein structural bioinformatics and protein structural evolution, examine how ligand-binding equilibria may form the basis of diverse biological phenomena, learn the structure and properties of monosaccharides and polysaccharides and review the major types of lipids. This module develops key skills in analysis and interpretation of data, biochemical methodology and calculation of biochemical parameters.

To fully understand the function of biological systems, we must examine their underlying biochemical principles. You explore the importance of molecules which contain the p-block elements of oxygen, nitrogen, sulphur and phosphorus, concentrating on how their electron structure relates to the action of redox enzymes in metabolism. You also look at the biological role of main-group and transition metal cations.

You will also review the physical elements of biochemical reactions, including kinetics and thermodynamics. You determine reaction rates, reaction orders and activation energies as well as assessing how thermodynamic parameters affect reactions.

The building blocks of life, plants and animals depend on the actions of individual cells. Investigate the biochemical characteristics of the small molecules and large macromolecules that allow cells to function. You examine the origins of life, cell structure and function, energy transductions, synthesis of molecules, and the eukaryotic cell cycle.

Microbes are essential for life, playing a vital role in connecting the health of humans, animals, and ecosystems. They aid in digestion, provide essential vitamins, and contribute significantly to our overall health and well-being. Marine microbes, for instance, produce approximately one-third of the oxygen we breathe. Additionally, microbes are indispensable for achieving the United Nations' Sustainable Development Goals, as they clean up pollutants and synthesize valuable products like antibiotics. However, not all microbes are beneficial - some cause devastating diseases. Despite significant advances in treatment and prevention, the incidence of infectious diseases continues to rise. In this module, you will explore the vast diversity and evolution of mostly beneficial microbes, alongside the pathogenicity of harmful ones. You will investigate how different viruses and bacteria invade, interact with, and replicate within their hosts. Through two practical sessions in our state-of-the-art teaching laboratory, you will study a food poisoning outbreak and will gain hands-on experience in growing, observing, purifying, counting, and even killing microbes. These sessions will equip you with highly sought-after skills, including aseptic technique, serial dilution, and data analysis.

Why do we all look different? Are some illnesses hereditary? Are animals born ready-suited to their environment? From the early theories of Mendel to modern studies in molecular genetics, you explore how scientists have answered these questions over the last 150 years. Examine how the structure and function of DNA allows genetic material to be expressed, replicated and inherited, and consider how genetic variation leads to adaptive evolution. From developing new technologies in gene cloning to the applications for modern medicine, you explore how geneticists are building on the earlier achievements in this fundamentally important field to enhance our understanding of life on earth.

You will develop your transferable skills in scientific writing (including referencing and avoiding plagiarism), teamwork and communication through oral presentations, study and research skills (including essay writing, lecture note taking, use of library and databases). Teaching and learning will be through a mixture of lectures, classes, and tutorials. The emphasis will be on small group, tutorial-style teaching and interaction with other students on this module, with assessments tailored to your degree subject area.