MPhil Cardiovascular Sciences

University of Manchester

Our PhD/MPhil Cardiovascular Sciences programme enables you to undertake a research project that will improve understanding of Cardiovascular Sciences. Cardiovascular diseases are major causes of mortality and morbidity in developed and developing countries worldwide. Our research spans five main themes: cardiovascular genetics and development; experimental cardiology; vascular biology/hypertension; stroke; clinical cardiovascular research; We adopt an integrated 'bench-to-bedside' translational approach for understanding the underlying mechanisms responsible for the functioning of the cardiovascular system in both health and disease. To this end, there is a wide spectrum of research spanning clinical trials, small and large animal models of cardiovascular diseases, whole organs and tissues, cells and single molecule studies. Working together in purpose-built facilities provides for a stimulating and cutting-edge environment. Examples of research programmes include: cardiac and vascular electrophysiology; cardiac conduction system; calcium and second messenger signalling in the heart and vasculature; heart failure and arrhythmias; hypertrophic signalling pathways in the heart; cardiovascular genetics and development; cellular and protein structure; comparative biology and mitochondrial function; computer modelling; hypertension, obesity, metabolic syndrome and diabetes research; vascular biology of small and large arteries; angiogenesis and endothelial biology; stroke; cardiovascular imaging; induced Pluripotent Stem Cell (iPSC) models of cardiovascular disease; cardiac and vascular regeneration; renal physiology and genetics; renal medicine.