Students on the ‘Inflammation PhD’ Programme will be studying for their PhD under supervision of a Principal Investigator of the Centre for Inflammation Research (CIR). CIR, which is directed by Prof David Dockrell, Chair of Infection Medicine, is part of the Institute for Regeneration and Repair (IRR). Scientists and clinician scientists in the Centre for Inflammation Research study processes related to the initiation, regulation and resolution of acute and chronic inflammation, including those caused by pathogens and microbiota and the prevention, diagnosis and treatment of inflammatory and infectious diseases. Acute inflammation is a critical part of the body’s response to infection and required for tissue homeostasis and the response to infectious diseases, while chronic inflammatory disorders are a major cause of morbidity and mortality worldwide. Chronic inflammation promotes tissue and organ fibrosis with adverse functional consequences. Research in the CIR addresses the critical need to identify therapeutic targets in inflammation and infection, new approaches to imaging inflammation and fibrosis and aims to translate these developments to clinical applications. Research topics within CIR cover many areas, including: development of inflammatory cells the microbiome autoimmunity the role of inflammatory responses in respiratory, hepatic, renal, skin and neurological diseases and cancer biology development and regulation of immunity and host-pathogen interactions the initiation, regulation and resolution of inflammatory responses. CIR aims to promote the prevention, diagnosis and treatment of inflammatory and infectious diseases through interdisciplinary study and by providing an outstanding environment for research training in the field. For a full description of research groups and their topics, visit the research profiles of CIR Principal Investigators: CIR Research *(Revised 5 December 2024 to update areas of research)