Cross-talk between the nervous and immune systems is critical for survival, and disrupted neuro-immune communication is observed in many debilitating conditions, including chronic inflammatory, neurodegenerative and psychiatric diseases. To better understand these conditions, we urgently need a new generation of interdisciplinary researchers that can work across the neuro-immune spectrum. The Wellcome Trust ‘Neuro-Immune Interactions in Health & Disease’ PhD Training Programme is designed to provide the requisite training, using state-of-the-art technologies, cutting-edge science and supervision methods. In line with Wellcome’s new Research Culture (#ReimagineResearch), we are committed to provide scientific excellence in a positive working environment. Our programme will develop and share practices that bring science and culture together, placing both firmly at the heart of our training strategy and your research journey.