Our major areas of research interest are: cellular and molecular mechanisms of the resolution and persistence of lung inflammation and scarring mechanisms of acute lung injury in the adult respiratory distress syndrome gene therapeutic approaches to the augmentation of genes that protect against tissue injury in lung inflammation biology of small-cell lung cancer the effects of cigarette smoke, ozone and other pollutants on the lung sleep apnoea applied lung physiology The unit also offers a number of research opportunities in areas of clinical interest, for example: asthma chronic bronchitis emphysema cystic fibrosis