One year of supervised laboratory-based research examined by thesis and an oral examination. This is not a taught course. Applicants are typically science postgraduates or clinically qualified doctors undertaking scientific training. Research is predominantly in the areas of cancer genetics and the genetics of rare disease and developmental disorders. The aim is to understand the cell biology of disease mechanisms using a wide range of disciplines including biochemistry, genetics, molecular biology, cell biology, bioinformatics and biostatistics. Specific research training relevant to your own project is provided in the laboratory in which you work. Further training is provided within the Addenbrooke's campus and elsewhere in the University, and includes postgraduate workshops on research techniques, research seminars, and postgraduate student education seminars on generic subjects such as intellectual property rights, statistics, bioinformatics, communication skills, writing a thesis or paper and entrepreneurship.The course's main aims are:to give students with relevant experience at first-degree level the opportunity to carry out focused research in the discipline under close supervision andto give students the opportunity to acquire or develop skills and expertise relevant to their research interests.Learning OutcomesBy the end of the programme, students will have:* a comprehensive understanding of techniques, and a thorough knowledge of the literature, applicable to their own research* demonstrated originality in the application of knowledge, together with a practical understanding of how research and enquiry are used to create and interpret knowledge in their field* shown abilities in the critical evaluation of current research and research techniques and methodologies* demonstrated some self-direction and originality in tackling and solving problems, and acted autonomously in the planning and implementation of research.ContinuingThose who wish to progress to a PhD after completing an MPhil will be required to satisfy their potential supervisor, Head of Department and the Faculty Degree Committee that they have the skills and ability to achieve the higher degree, and have the required funding in place for further study.